APOCYNIN, A SELECTIVE NADPH OXIDASE (NOX2) INHIBITOR, AMELIORATES BEHAVIOURAL AND LEARNING DEFICITS IN THE FRAGILE X SYNDROME MOUSE MODEL

Apocynin, a Selective NADPH Oxidase (Nox2) Inhibitor, Ameliorates Behavioural and Learning Deficits in the Fragile X Syndrome Mouse Model

Background/Objectives: Fragile X Syndrome (FXS) is associated with intellectual disability, hyperactivity, social anxiety and signs of autism.Hyperactivation of NADPH oxidase has been previously described in the brain of the male Fmr1-KO mouse.This work aims to demonstrate the efficacy of Apocynin, a specific NADPH oxidase inhibitor, in treating Fr

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Large-scale patterns of useful native plants based on a systematic review of ethnobotanical studies in Argentina

Plants are essential for our lives because they provide food, medicine, fuel, shelter, and immaterial resources.Understanding patterns of plant uses through large-scale plant use analysis may contribute to the development of a biocultural conservation approach.We conducted a systematic review to assess current knowledge of the ethnoflora of Argenti

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From System Modeling to System Analysis: The Impact of Resolution Level and Resolution Distribution in the Computer-Aided Investigation of Biomolecules

The ever increasing computer power, together with the improved accuracy of atomistic force fields, enables Reception Desks researchers to investigate biological systems at the molecular level with remarkable detail.However, the relevant length and time scales of many processes of interest are still hardly within reach even for state-of-the-art hard

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